Suggested reading

Publications of Prof. Dr. med. S. Dieterle (from 2010)

Ribosomal DNA methylation in human and mouse oocytes increases with age.

Potabattula R, Trapphoff T, Dittrich M, Fic K, Ptak G, Dieterle S, Haaf T. (2022). Aging, 14 (3):1214-1232.

Impact of Nonylphenols and Polyhalogenated Compounds in Follicular Fluid on the Outcome of Intracytoplasmic Sperm Injection.

Bullach A, Trapphoff T, Zühlke S, Spiteller M, Dieterle S. (2021). Reproductive Sciences, 28(8), 2118-2128

 

rDNA methylation of human oocytes of women undergoing intracytoplasmic sperm injection (ICSI) increases with maternal age.

Trapphoff T, Dieterle S, Potabattula R, Haaf T. (2021). Human Reproduction, 36(1), i377-i378

 

Analyse von Schadstoffen aus dem Konsum von Tabakprodukten oder nikotinhaltigen Substanzen in der Follikelflüssigkeit (FF) von Frauen im Rahmen einer intrazytoplasmatischen Spermieninjektion (ICSI)-Behandlung.

Trapphoff T, Ontrup C, Dieterle S. (2021). Journal of Reproductive Medicine and Endocrinology, 18(5), 249

 

Analysis of Nonylphenols (NPs), Mirex and selected endocrine disrupting chemicals (EDCs) in the follicular fluid (FF) of women undergoing intracytoplasmic sperm injection (ICSI).

Trapphoff T, Bullach A, Zuehlke S, Spiteller M, Dieterle S. (2020). Human Reproduction, 35, i391-i391

 

Endometriose und Kinderwunsch – was ist wirklich sinnvoll?L. Söhngen, S. Dieterle Gynäkologische Praxis 2017, 42:199-207

 

Zika-Virus-Infektion in der Gynäkologie und GeburtshilfeI.Mylonas, S. Dieterle, M. Hampl, U. Hoyme, J. Jückstock, W. Mendling, G. Neumann, K. FrieseDer Gynäkologe 2016, 49:786-794

 

Akupunktur bei Kinderwunsch [Acupuncture in the desire to have children]

K. Friol, C. Gnoth, F. Sulistyo, S. DieterleDer Gynäkologe 2015, 48:36-43, ©Springer-Verlag Berlin Heidelberg 2014

Thyroid autoantibodies per se do not impair intracytoplasmatic sperm injection outcome in euthyroid healthy women

Susanne Tan, Stefan Dieterle, Sonali Pechlavanis, Onno E. Janssen, Dagmar FuhrerEuropean Journal of Endocrinology (2014) 170, 495-500

Assistierte Reproduktion - Wege zum Wunschkind [Assisted reproduction - The way to your desired child]

Prof. Dr. med. Stefan DieterleUro-News 2013; 17 (6): 21-24, (Springer Medizin, Urban & Vogel GmbH, 2013)

Thyroid autoimmunity does not impair assisted reproductive technology outcome in fertile women.

Tan S, Janssen OE, Lahner H, Moeller LC, Hertel S, Pechlivanis S, Seebauer J, Mann K, Führer D, Dieterle S. 55. Symposium der Deutschen Gesellschaft für Endokrinologie, Mannheim (08.03.2012)Quality and Risk Management in In vitro fertilization. Meeting "ART and clinical: towards a more successful and safer ART"Dieterle S, Bierhals K.Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (29.10.2011).

Stadienabhängige Fertilitätseinschränkung bei peritonealer und tiefinfiltrierender Endometriose: Welche Mechanismen werden durch die in vitro Fertilisation erkennbar? [Stage-dependent limitations of fertility in peritoneal and deep infiltrating endometriosis: which mechanisms can be recognised through in-vitro fertilisation?]

Kubiak A, Dieterle S, Neuer A, Bierhals K, Greb R. 9. Endometriosis conference of the German-speaking countries, Emmendingen (1 June 2011). Geburtsh Frauenheilk (2011); 71: 464

Acupuncture for infertility: is it an effective therapy?

Huang DM, Huang GY, Lu FE, Dieterle S, Neuer A, Greb R.Chin J Integr Med. 2011 May;17(5):386-95. Epub 2011 May 25. Review.

How to make a good embryo

Dieterle S, Schlösser V.International Academic Symposium. Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China (18.10.2010).

Desquamated epithelial cells covered with a polymicrobial biofilm typical for bacterial vaginosis are present in randomly selected cryopreserved donor semen.

Swidsinski A, Dörffel Y, Loening-Baucke V, Mendling W, Verstraelen H, Dieterle S, Schilling J.FEMS Immunol Med Microbiol. 2010 Aug;59(3):399-404. Epub 2010 Apr 20.

Genetic polymorphism in an inflammasome component, cervical mycoplasma detection and female infertility in women undergoing in vitro fertilization.

Witkin SS, Bierhals K, Linhares I, Normand N, Dieterle S, Neuer A.J Reprod Immunol. 2010 Mar;84(2):171-5. Epub 2010 Jan 8.

Publications of Dr. med A. Neuer (from 2010)

Stadienabhängige Fertilitätseinschränkung bei peritonealer und tiefinfiltrierender Endometriose: Welche Mechanismen werden durch die in vitro Fertilisation erkennbar? [Stage-dependent limitations of fertility in peritoneal and deep infiltrating endometriosis: which mechanisms can be recognised through in-vitro fertilisation?]

Kubiak A, Dieterle S, Neuer A, Bierhals K, Greb R. 9. Endometriosis conference of the German-speaking countries, Emmendingen (1 June 2011). Geburtsh Frauenheilk (2011); 71: 464

Genetic polymorphism in an inflammasome component, cervical mycoplasma detection and female infertility in women undergoing in vitro fertilization.

Witkin SS, Bierhals K, Linhares I, Normand N, Dieterle S, Neuer A.J Reprod Immunol. 2010 Mar;84(2):171-5. Epub 2010 Jan 8.

Publikationen
Dr. rer. nat. Tom Trapphoff
(ab 2010)

Ribosomal DNA methylation in human and mouse oocytes increases with age.

Potabattula R, Trapphoff T, Dittrich M, Fic K, Ptak G, Dieterle S, Haaf T. (2022). Aging, 14 (3):1214-1232.

Impact of Nonylphenols and Polyhalogenated Compounds in Follicular Fluid on the Outcome of Intracytoplasmic Sperm Injection.

Bullach A, Trapphoff T, Zühlke S, Spiteller M, Dieterle S. (2021). Reproductive Sciences, 28(8), 2118-2128

 

rDNA methylation of human oocytes of women undergoing intracytoplasmic sperm injection (ICSI) increases with maternal age.

Trapphoff T, Dieterle S, Potabattula R, Haaf T. (2021). Human Reproduction, 36(1), i377-i378

 

Analyse von Schadstoffen aus dem Konsum von Tabakprodukten oder nikotinhaltigen Substanzen in der Follikelflüssigkeit (FF) von Frauen im Rahmen einer intrazytoplasmatischen Spermieninjektion (ICSI)-Behandlung.

Trapphoff T, Ontrup C, Dieterle S. (2021). Journal of Reproductive Medicine and Endocrinology, 18(5), 249

 

COVID-19 in ART-Laboratory.

Trapphoff T, Gutknecht D, Kienast K, Baston-Büst D, Nordhoff V. (2021). Journal of Reproductive Medicine and Endocrinology, 18(1), 33-37

 

Leitlinie für die Führung und Einrichtung eines Labors für die Durchführung ­Assistierter Reproduktionstechnologien beim Menschen (ART-Labor) innerhalb einer reproduk­tionsmedizinischen Versorgungseinrichtung der Arbeitsgemeinschaft Reproduktions­biologie.

Gutknecht D, Blumenauer V, Hauff B, Klusmann P, Trapphoff T, Weiss D. (2020). AGRBM Qualitätsmanagement

 

Analysis of Nonylphenols (NPs), Mirex and selected endocrine disrupting chemicals (EDCs) in the follicular fluid (FF) of women undergoing intracytoplasmic sperm injection (ICSI).

Trapphoff T, Bullach A, Zuehlke S, Spiteller M, Dieterle S. (2020). Human Reproduction, 35, i391-i391

 

Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.

Trapphoff T, Heiligentag M, Dankert D, Demond H, Deutsch D, Fröhlich T, Arnold G, Grümmer R, Horsthemke B, Eichenlaub-Ritter U. (2016). Human Reproduction, 31(1), 133-149

 

Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification.

Trapphoff T, Heiligentag M, Simon J, Staubach N, Seidel T, Otte K, Fröhlich T, Arnold G, Eichenlaub-Ritter U. (2016). Molecular Human Reproduction, 22(12), 867-881

 

Preovulatory aging in vivo and in vitro affects maturation rates, abundance of selected proteins, histone methylation pattern and spindle integrity in murine Oocytes.

Demond H, Trapphoff T, Dankert D, Heiligentag M, Grümmer R, Horsthemke B, Eichenlaub-Ritter U. (2016). PLoS ONE, 11(9), doi.org/10.1371/journal.pone.0162722

 

Activator of fatty acid metabolism (AICAR) improves maturation rate, but affects spindle formation and chromosome integrity in in vitro maturing denuded mouse oocytes.

Eichenlaub-Ritter U, Betzendahl I, Trapphoff T, Drechsler C, Heiligentag M. (2015). Human Reproduction, 30(1), i301-i302

 

Histone H4 lysine 12 (H4K12) acetylation state as epigenetic marker of quality of oocytes from in vitro maturation (IVM).

Heiligentag M, Trapphoff T, Kalhori S, Drechsler C, Betzendahl I, Eichenlaub-Ritter U. (2015). Human Reproduction, 30(1), i85-i86

 

Vitrification of oocytes: Imprinting and disturbance in spindle formation and chromosome segregation.

Trapphoff T. (2015). Vitrification in Assisted Reproduction, Second Edition. Edited by Tucker & Liebermann, CRC Press, ISBN 9780429185816

 

Proteome, survival rate and developmental potential of control and vitrified mouse oocytes matured with or without a glutathione donor.

Heiligentag M, Trapphoff T, Simon J, Betzendahl I, Fröhlich T, Arnold G, Eichenlaub-Ritter U. (2014). Human Reproduction, 29(1), i172

 

Loss of Msy2-mRNA interaction might affect transcript level and poly(A) tail lenght of MEG after postovulatory aging in mouse MII oocytes.

Trapphoff T, Heiligentag M, Eichenlaub-Ritter U. (2014). 25. Jahrestagung der Deutschen Gesellschaft für Humangenetik

 

Poly(A) tail length of maternal-effect gene mRNAs in oocytes is influenced by postovulatory aging.

Dankert D, Demond H, Trapphoff T, Heiligentag M, Eichenlaub-Ritter U, Horsthemke B, Gruemmer R. (2014). Human Reproduction, 29(1), i98-i99

 

Altered expression and localization of maternal proteins and changes in histone pattern after preovulatory and postovulatory ageing of mammalian oocytes.

Trapphoff T, Demond H, Dankert D, Heiligentag M, Betzendahl I, Grümmer R, Horsthemke B, Eichenlaub-Ritter U. (2014). Human Reproduction, 29(1), i94

 

Pre- and postovulatory aging of murine oocytes affect the transcript level and poly(A) tail length of maternal effect genes.

Dankert D, Demond H, Trapphoff T, Heiligentag M, Rademacher K, Eichenlaub-Ritter U, Horsthemke B, Grümmer R. (2014). PLoS ONE, 9(10), doi.org/10.1371/journal.pone.0108907

 

Acetylation of Histone H4 Lysine 12 as a Marker for Metaphase II Oocyte quality and in improving in vitro Maturation.

Kalhori S, Heiligentag M, Trapphoff T, Eichenlaub-Ritter U. (2013). Journal of Reproductive Medicine and Endocrinology, 10(5-6), 318-319

 

Influence of L-Carnitine on the Mitochondrial Metabolism and Maturation Characteristics of Murine Oocytes.

Simon J, Trapphoff T, Heiligentag M, Eichenlaub-Ritter U. (2013). Journal of Reproductive Medicine and Endocrinology, 10(5-6), 317

 

Maturation in presence of a glutathione donor protects spindle integrity and chromosomal alignment in vitrified mouse metaphase II oocytes.

Trapphoff T, Staubach N, Seidel T, Heiligentag M, Eichenlaub-Ritter U. (2013). Human Reproduction, 28(1), i112-i115.

 

Transcript level and Poly(A) Content of maternal effect Genes, Spindle Constitution and epigenetic Histone modifications are influenced by pre- and postovulatory Ageing in Mouse Metaphase II Oocytes.

Demond H, Dankert D, Trapphoff T, Heiligentag M, Grümmer R, Eichenlaub-Ritter U, Horsthemke B. (2013). Journal of Reproductive Medicine and Endocrinology, 10(5-6), 315-316

 

Chronic exposure to a low concentration of bisphenol A during follicle culture affects the epigenetic status of germinal vesicles and metaphase II oocytes.

Trapphoff T, Heiligentag M, El Hajj N, Haaf T, Eichenlaub-Ritter U. (2013). Fertility and Sterility, 100(6), 1758-1767

 

Supplementation of Glutathione Ethylester Protects Spindle and Chromosomal Integrity in vitrified in vitro and in vivo matured Oocytes.

Heiligentag M, Trapphoff T, Seidel T, Arnold G, Eichenlaub-Ritter U. (2013). Journal of Reproductive Medicine and Endocrinology, 10(5-6), 315

 

Mitochondrial redox profile after CryoTop vitrification of in vitro matured murine metaphase II oocytes or germinal vesicle oocytes from preantral follicles.

Trapphoff T, Staubach N, Simon J, Treffon P, Eichenlaub-Ritter U. (2012). 55. Symposium - Deutsche Gesellschaft für Endokrinologie, 4

 

Low dose exposure to bishenol A accelerates follicle development and interferes with imprint establishment in oocytes during mouse preantral follicle culture.

Eichenlaub-Ritter U, Trapphoff T, Hastreiter S, Haaf T. (2012). Human Reproduction, 27(2), i286-i302

 

Mitochondrial redox potential and inner membrane potential, and proteomes of oocytes from control and vitrified mouse preantral follicles.

Trapphoff T, Demant M, Staubach N, Fröhlich T, Arnold G, Eichenlaub-Ritter U. (2012). Human Reproduction, 27(2), i41-i44

 

Endoplasmic reticulum-derived multilamellar bodies in oocytes of mouse follicle cultures under oxidized low-density lipoprotein treatment.

Spanel-Borowski K, Nowicki M, Borlak J, Trapphoff T, Eichenlaub-Ritter U. (2012). Cells Tissues Organs, 197(1), 77-88

 

Vitrification at the pre-antral stage transiently alters inner mitochondrial membrane potential but proteome of in vitro grown and matured mouse oocytes appears unaffected.

Demant M, Trapphoff T, Fröhlich T, Arnold G, Eichenlaub-Ritter U. (2012). Human Reproduction, 27(4), 1096-1111

 

Non-Invasive Assessment of Inner Mitochondrial Redox Potential of Vitrified Metaphase II Oocytes or Germinal Vesicle Oocytes Vitrified Within Preantral Follicles.

Trapphoff T, Treffon P, Staubach N, Eichenlaub-Ritter U. (2011). Journal of Reproductive Medicine and Endocrinology, 8(5), 323

 

Limiting dilution bisulfte (pyro)sequencing reveals parent-specific methylation patterns in single early mouse embryos and bovine oocytes.

El Hajj N, Trapphoff T, Linke M, May A, Hansmann T, Kuhtz J, Reifenberg K, Heinzmann J, Niemann H, Daser A, Eichenlaub-Ritter U, Zechner U, Haaf T. (2011). Epigenetics, 6(10), 1176-1188

 

Influence of vitrification on spindle, genetic constitution, epigenetic profile and developmental capacity of in vitro grown mouse oocytes.

Trapphoff T, El Hajj N, Haaf T, Eichenlaub-Ritter U. (2010). Human Reproduction, 25(1), doi.org/10.1093/humrep/de.25.s1.2

 

Proteome profile of oocytes to assess gene expression at proteome level and influences of vitrification.

Trapphoff T, Demant M, Arnold G, Eichenlaub-Ritter U. (2010). Journal of Reproductive Medicine and Endocrinology, 7(4), 362

 

Chromosomal and cytoplasmic context determines predisposition to maternal age-related aneuploidy: Brief overview and update on MCAK in mammalian oocytes.

Eichenlaub-Ritter U, Staubach N, Trapphoff T. (2010). Biochemical Society Transactions, 38(6), 1681-1686

 

DNA integrity, growth pattern, spindle formation, chromosomal constitution and imprinting patterns of mouse oocytes from vitrified pre-antral follicles.

Trapphoff T, El Hajj N, Zechner U, Haaf T, Eichenlaub-Ritter U. (2010). Human Reproduction, 25(12), 3025-3042